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The MISM Center of Excellence develops bridging frameworks for infectious and immune-mediated disease (IID) models across biological scales from molecules to populations. Our goal is to unify experimental, computational, clinical, and epidemiological data into predictive, interpretable models of immune function and disease dynamics. The primary goal of MISM is to enable multiscale modeling through our research and coordination with the larger IID modeling community. 
Our scientific goals are guided by three Research Projects focused on developing bridging frameworks, and supported by three Cores that facilitate goal achievement and Center operations.

 


RESEARCH PROJECTS

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Research Project 1 (RP1)

Integrating Atomic-Scale Antigen Modeling and Repertoire-Scale Protein Language Models 

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Research Project 2 (RP2)

Bridging Cell and Organism Scales to Model Viral, Cell, and Microenvironmental Determinants of Infection Outcome 

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Research Project 3 (RP3)

Immune Response, Transmission Model, and Contact Network Determinants of Disease Spread 

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CORES

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Administrative Core (AC)

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Community Development and Education Core (CDEC)

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Model and Data Sharing Core (MDSC)

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