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 Proposals with a MISM focus. Generate your ideas on well-defined, high-priority areas of research relevant to the MISM overall mission.

The Multiscale Immune System Modeling (MISM) Center is pleased to announce the inaugural annual MISM Pilot Award Request for Proposal, due January 31, 2026, 5:00pm EST.

Through this funding opportunity announcement, we aim to encourage new and unique projects and collaborations bridging across biological scales that 1) address fundamental gaps in our mechanistic understanding of immune-related health and disease and 2) provide in silico laboratories evaluating prophylactic and therapeutic interventions.

The full RFP can be found here, and application submission instructions are below:

A Letter of Intent (LOI) is required to submit a MISM Pilot Grant. LOIs are mandatory and will be used to determine appropriateness for the RFA, provide feedback to submitters, aid the recruitment of appropriately knowledgeable reviewers, and for other review planning. LOIs should include the following information:

  1. Name and email of the Principal Investigator(s)
  2. Names of other key personnel and Institution/Department/Division Affiliation
  3. Descriptive title of proposed research
  4. Abstract (less than 350 words) describing hypotheses and aims
  5. LOIs should be emailed to MISM@duke.edu

MISM uses the MyResearchProposal online application software to submit full applications.

  • To apply visit https://duke.is/DukeMRP, click on “Create New Account” (or log in if you already have an account). Proposals must be submitted under the Primary Applicant’s name.
  • A step-by-step user’s guide for applying via the MyResearchProposal software is available here.
  • Enter Access Code ‘MISM’ in the search box in the upper right-hand corner and scroll down the page and select the “MISM Pilot Award 2025” and follow the instructions.
  • For any questions concerning MyResearchProposal passwords or system issues, please contact myresearchproposal@duke.edu.

One-year awards are intended to facilitate Early-Stage Investigatory research by providing modest, but essential resources. Funds are typically used to generate preliminary data for a planned NIH grant application or to address weaknesses in a previously submitted, unscored proposal. 

Available Funding Opportunities 

PILOT GRANTS