Co-Lead, Research Project 1, MISM
Asst. Professor in Biostatistics & Bioinformatics, Duke
Rohit Singh, PhD, Project Co-Lead, is an Assistant Professor in the Department of Biostatistics & Bioinformatics and Cell Biology at Duke University. His research interests are broadly in computational biology, with a focus on using machine learning to make drug discovery more efficient. Dr. Singh brings a wealth of expertise in computational biology and has pioneered techniques in protein language models (PLMs) and single-cell genomics to MISM. His current research explores how single-cell genomics and large language models can help decode disease mechanisms and identify new targets and drugs. Dr. Singh is the recipient of the Test of Time Award at RECOMB, MIT's George M. Sprowls Award for his PhD thesis in Computer Science, and Stanford's Christopher Stephenson Memorial Award for Master’s Research in the same field. In addition to academia, he has industry experience.
He will manage MISM Research Project 1 (RP1) and lead the design of the machine learning framework for B-cell receptor (BCR) repertoire analysis, and integrate these algorithmic advancements into a multiscale model of viral escape. As a faculty member and industry leader with a track record of successful project leadership, Dr. Singh’s involvement is crucial to maintaining a close connection between the experimental and computational aspects of RP1 and to developing scientific tools for better pandemic preparedness.